Publications
Selected Recent Publications
Lentzsch AM, Yudin D, Gamerdinger M, Chandrasekar S, Rabl L, Scaiola A, Deuerling E, Ban N, Shan SO. NAC guides a ribosomal multienzyme complex for nascent protein processing. Nature. 2024 Aug 21. doi: external page 10.1038/s41586-024-07846-7. external page Open access
Gamerdinger M, Jia M, Schloemer R, Rabl L, Jaskolowski M, Khakzar KM, Ulusoy Z, Wallisch A, Jomaa A, Hunaeus G, Scaiola A, Diederichs K, Ban N, Deuerling E. NAC controls cotranslational N-terminal methionine excision in eukaryotes. Science. 2023 Jun 23;380(6651):1238-1243. doi: external page 10.1126/science.adg3297
Saurer M, Leibundgut M, Nadimpalli HP, Scaiola A, Schönhut T, Lee RG, Siira SJ, Rackham O, Dreos R, Lenarčič T, Kummer E, Gatfield D, Filipovska A, Ban N. Molecular basis of translation termination at noncanonical stop codons in human mitochondria. Science. 2023 May 5;380(6644):531-536. doi: external page 10.1126/science.adf9890. external page Open access
Bhatt PR, Scaiola A, Loughran G, Leibundgut M, Kratzel A, Meurs R, Dreos R, O'Connor KM, McMillan A, Bode JW, Thiel V, Gatfield D, Atkins JF, Ban N. Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome. Science. 2021 Jun 18;372(6548):1306-1313. doi: external page 10.1126/science.abf3546
Greber BJ, Bieri P, Leibundgut M, Leitner A, Aebersold R, Boehringer D, Ban N. Ribosome. The complete structure of the 55S mammalian mitochondrial ribosome. Science. 2015 Apr 17;348(6232):303-8. doi: external page 10.1126/science.aaa3872
Kummer E, Leibundgut M, Rackham O, Lee RG, Boehringer D, Filipovska A, Ban N. Unique features of mammalian mitochondrial translation initiation revealed by cryo-EM. Nature. 2018 Aug;560(7717):263-267. doi: external page 10.1038/s41586-018-0373-y
Kobayashi K, Jomaa A, Lee JH, Chandrasekar S, Boehringer D, Shan SO, Ban N. Structure of a prehandover mammalian ribosomal SRP·SRP receptor targeting complex. Science. 2018 Apr 20;360(6386):323-327. doi: external page 10.1126/science.aar7924. external page Open access
Ramrath DJF, Niemann M, Leibundgut M, Bieri P, Prange C, Horn EK, Leitner A, Boehringer D, Schneider A, Ban N. Evolutionary shift toward protein-based architecture in trypanosomal mitochondrial ribosomes. Science. 2018 Oct 26;362(6413):eaau7735. doi: external page 10.1126/science.aau7735. external page Open access
Schubert K, Karousis ED, Jomaa A, Scaiola A, Echeverria B, Gurzeler LA, Leibundgut M, Thiel V, Mühlemann O, Ban N. SARS-CoV-2 Nsp1 binds the ribosomal mRNA channel to inhibit translation. Nat Struct Mol Biol. 2020 Oct;27(10):959-966. doi: external page 10.1038/s41594-020-0511-8
Saurer M, Ramrath DJF, Niemann M, Calderaro S, Prange C, Mattei S, Scaiola A, Leitner A, Bieri P, Horn EK, Leibundgut M, Boehringer D, Schneider A, Ban N. Mitoribosomal small subunit biogenesis in trypanosomes involves an extensive assembly machinery. Science. 2019 Sep 13;365(6458):1144-1149. doi: external page 10.1126/science.aaw5570. external page Open access
Kummer E, Ban N. Mechanisms and regulation of protein synthesis in mitochondria. Nat Rev Mol Cell Biol. 2021 May;22(5):307-325. doi: external page 10.1038/s41580-021-00332-2
Tetter S, Terasaka N, Steinauer A, Bingham RJ, Clark S, Scott AJP, Patel N, Leibundgut M, Wroblewski E, Ban N, Stockley PG, Twarock R, Hilvert D. Evolution of a virus-like architecture and packaging mechanism in a repurposed bacterial protein. Science. 2021 Jun 11;372(6547):1220-1224. doi: external page 10.1126/science.abg2822